Septoria Leaf Spot
Agent: Septoria lycopersici

Symptoms
Forms light spots with dark edges, with black dots inside. Later the leaf yellows and falls off. Does not affect fruits. The fungus is resistant, survives winter.
Control and prevention
Remove and destroy affected leaves. Prevention: drip irrigation, good ventilation. If attacked - fungicides.
Related problems
Similar symptoms might indicate a different cause — compare them.

Early blight and black fruit rot
Alternaria solani
Usually appears when fruits begin to set. First affects the lower leaves, then the stem and fruits. Large brown or black spots with concentric rings appear on them. Around the spot, the leaf begins to yellow and dies. It also attacks potatoes and eggplants. The fungus is resistant and persists for several years.

Late blight
Phytophthora infestans
Dark green or black spots appear and spread on the edges of the leaves. The same can appear on the fruits.

Root Rot
Fusarium oxysporum
Common in tomato gardens. Thrives in warm, acidic soils. Infects the plant through the roots, spreads through the circulatory system. The first symptom is yellowing of the lower leaves; dark brown spots are found when the stem is cut. Can affect potatoes, peppers, eggplants.